The successful SFEBq-driven retina growth, including the development of the optic vesicle and its structural collapse to form the optic cup, demonstrates that building and shaping of a retina can occur without support from neighboring tissues such as lens cell. In the words of Yoshika Sasai, a neurobiologist at RIKEN Center for Develiopment Biology in Kobe, Japan , “retinal formation, at least in vitro, is a self-organizing phenomenon based on an internal program that resides within these cells.”
Keywords: molecular neurobiology, organogenesis, neurogenesis, compound tissue, neuroepithelium, mammalian embryogenesis, embryonic stem cells.
References, cell-adhesion figures, schematic diagram and further reading
 M. Eiraku , N. Takata, H. Ishibashi, M. Kawada, E. Sakakura, S. Okuda, K. Sekiguchi, T. Adachi and Y. Sasai: Self-organizing optic-cup morphogenesis in three-dimensional culture. Nature April 7, 2011, 472, 51-56.
 Kurzweil Accelerating Intelligence: Stem cells used to create retinal tissue. April 7, 2011 [www.kurzweilai.net/stem-cells-used-to-create-retinal-tissue].
 M. Eiraku and Y. Sasai: Mouse embryonic stem cell culture for generation of three-dimensional retinal and cortical tissues. Nature Protocols 2012, 7, 69-79.
 Y. Sasai: Grow Your Own Eye. Scientific American November 2012, 307 (5), 44-49.