Tuesday, November 24, 2009

Acronym in biochemistry: CALB for Candida antarctica lipase B

CALB stands for the enzyme lipase B specificly isolated from the yeast-like fungus Candida antarctica. CALB exhibits hydrolytic, ester synthesis and transesterification activity. It is a versatile biocatalyst, for example in asymmetric synthesis.
The structure and activity of CALB is currently investigated in various media including water, organic solvents, and ionic liquids as well as in solvent-free processing.

Keywords: organic chemistry, green chemistry, biocatalysis

Selected literature
[1] Kwang-Wook Kim, Boyoung Song, Min-Young Choi and Mahn-Joo Kim: Biocatalysis in Ionic Liquids: Markedly Enhanced Enantioselectivity of Lipase. Org. Lett. 2001, 3 (10), pp. 1507-1509. PDF-version.
[2] Francesco Secundo and Giacomo Carrea: Lipase activity and conformation in neat organic solvents. J. Mol. Catal. B: Enzym. December 2002, 19-20, pp. 93-102.
DOI: 10.1016/S1381-1177(02)00155-8.
[3] Anil Mahapatro, Ajay Kumar, Bhanu Kalra and Richard A. Gross: Solvent-free Adipic Acid/1,8-Octanediol Condensation Polymerizations Catalyzed by Candida antarctica Lipase B. Macromolecules 2004, 37, pp. 35-40. PDF-version.
[4] Hua Zhao, Cecil L. Jones and Janet V. Cowins: Lipase dissolution and stabilization in ether-functionalized ionic liquids. Green Chem. 2009, 11, pp. 1128-1138. DOI: 10.1039/b905388c.

No comments:

Post a Comment